Omicron sublineage BA.2 remains a variant of concern

BA.2 should also remain classified as Omicron, WHO’s Technical Advisory Group on SARS-CoV-2 Virus Evolution (TAG-VE)  which was held yesterday. 

SARS-CoV-2 is the coronavirus that causes COVID-19, and the expert group meets regularly to discuss available data on transmissibility and severity of variants as well as their impact on diagnostics, therapeutics, and vaccines. 

They stressed that public health authorities should continue to monitor BA.2 as a distinct sublineage of Omicron, currently the dominant variant circulating globally. 

Studies underway 

Omicron is made up of several sublineages, including BA.1 and BA.2, all of which are being monitored by WHO and partners. 

BA.2 is among the most common, with reported sequences increasing in recent weeks, relative to BA.1, though global circulation of all variants is currently declining. 

The experts explained that BA.2 differs from BA.1 in its genetic sequence, and that it has a growth advantage over this sublineage.  

Although studies are ongoing to understand why, initial data suggest BA.2 appears inherently more transmissible than BA.1, currently the most common Omicron sublineage reported. 

However, this difference in transmissibility appears to be much smaller than that between BA.1 and the Delta variant, the experts said. 

Overall decline reported  

Meanwhile, although BA.2 sequences are increasing in proportion relative to other Omicron sublineages, there is still a reported decline in overall cases globally. 

Furthermore, while cases of reinfection with BA.2 following infection with BA.1 have been documented, preliminary data from studies show that infection with BA.1 provides strong protection against reinfection with BA.2. 

WHO will continue to closely monitor the BA.2 lineage as part of Omicron. 

The UN agency urged countries to remain vigilant, to monitor and report sequences, and to conduct independent and comparative analyses of the different Omicron sublineages. 

Globally, there were more than 424,820,000 cases of COVID-19 as of Tuesday, and more than 5.8 million deaths, according to WHO data.